Prognostic value of programmed cell death ligand-1 expression in breast cancer: A meta-analysis.

ABSTRACT:

Background

The correlation between programmed cell death-ligand 1 (PD-L1) which may affect T cell to form the immune tolerance and breast cancer (BC) still maintains to be uncovered. This meta-analysis was about to explore PD-L1 expression as well as its prognostic role in BC.

Methods

First of all, we performed 3 databases: PubMed, Embase, and Web of Science to explore publications between January of 2015 and January of 2020. Strict inclusion and exclusion criteria were conducted: immunohistochemistry shall be used to detect target molecule expression and at least 1 survival indicator and related data we need should be included. The hazard ratio and 95% confidence interval were pooled related with survival as well as clinicopathological parameters. The effects of PD-L1 in di

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC7717727 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature