Myocardial Infarction After High-Dose Catecholamine Application-A Case Report From an Experimental Imaging Study.

ABSTRACT: Although heart failure following myocardial infarction (MI) represents a major health burden, underlying microstructural and functional changes remain incompletely understood. Here, we report on a case of unexpected MI after treatment with the catecholamine isoproterenol in an experimental imaging study in mice using different state-of-the-art imaging modalities. The decline in cardiac function was documented by ultrahigh-frequency echocardiography and speckle-tracking analyses. Myocardial microstructure was studied ex vivo at a spatial resolution of 100 × 100 × 100 μm³ using diffusion tensor magnetic resonance imaging (DT-MRI) and histopathologic analyses. Two weeks after ISO treatment, the animal showed an apical aneurysm accompanied by reduced radial strain in correspo

SUBMITTER: Beyhoff N 

PROVIDER: S-EPMC7717942 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature