A Computational Phenotype of Disrupted Moral Inference in Borderline Personality Disorder.

ABSTRACT:

Background

Borderline personality disorder (BPD) is a serious mental disorder characterized by marked interpersonal disturbances, including difficulties trusting others and volatile impressions of others' moral character, often resulting in premature relationship termination. We tested a hypothesis that moral character inference is disrupted in BPD and sensitive to democratic therapeutic community (DTC) treatment.

Methods

Participants with BPD (n = 43; 20 untreated and 23 DTC-treated) and control participants without BPD (n = 106) completed a moral inference task where they predicted the decisions of 2 agents with distinct moral preferences: the "bad" agent was more willing than the "good" agent to harm others for money. Periodically, participants rated their subjective impr

SUBMITTER: Siegel JZ 

PROVIDER: S-EPMC7718209 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature