Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized ¹³ C MRSI.

ABSTRACT:

Purpose

With the initiation of human hyperpolarized ¹³ C (HP-¹³ C) trials at multiple sites and the development of improved acquisition methods, there is an imminent need to maximally extract diagnostic information to facilitate clinical interpretation. This study aims to improve human HP-¹³ C MR spectroscopic imaging through means of Tensor Rank truncation-Image enhancement (TRI) and optimal receiver combination (ORC).

Methods

A data-driven processing framework for dynamic HP ¹³ C MR spectroscopic imaging (MRSI) was developed. Using patient data sets acquired with both multichannel arrays and single-element receivers from the brain, abdomen, and pelvis, we examined the theory and application of TRI, as well as 2 ORC techniques: wh

SUBMITTER: Chen HY 

PROVIDER: S-EPMC7718428 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature