Neurological impact of emboli during adult cardiac surgery.

ABSTRACT:

Objectives

This study draws on advances in Doppler ultrasound bubble sizing to investigate whether high volumes of macro-bubbles entering the brain during cardiac surgery increase the risk of new cerebral microbleeds (CMBs), ischemic MR lesions, or post-operative cognitive decline (POCD).

Methods

Transcranial Doppler (TCD) ultrasound recordings were analysed to estimate numbers of emboli and macrobubbles (>100 μm) entering the brain during cardiac surgery. Logistic regression was used to explore the hypothesis that emboli characteristics affect the incidence of new brain injuries identified through pre- and post-operative MRI and neuropsychological testing.

Results

TCD, MRI, and neuropsychological test data were compared between 28 valve and 18 CABG patients. Although

SUBMITTER: Patel N 

PROVIDER: S-EPMC7718579 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature