Estimated Cost-effectiveness of Newborn Screening for Congenital Cytomegalovirus Infection in China Using a Markov Model.

ABSTRACT:

Importance

Congenital cytomegalovirus infection (cCMVi) is one of the most common infections associated with childhood hearing loss. Prevention and mitigation of cCMVi-related hearing loss will require an increase in newborn screening, which is not yet available in China.

Objective

To estimate the cost-effectiveness of newborn screening strategies for cCMVi from the perspective of the Chinese health care system.

Design, setting, and participants

A decision tree for a simulated cohort population of 15 000 000 live births was developed to compare the costs and health effects of 3 mutually exclusive interventions: (1) no screening, (2) targeted screening using CMV polymerase chain reaction assay for newborns who fail a universal hearing screening, and (3) universal scree

SUBMITTER: Chen K 

PROVIDER: S-EPMC7718603 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature