Fine-Grained Topography and Modularity of the Macaque Frontal Pole Cortex Revealed by Anatomical Connectivity Profiles.

ABSTRACT: The frontal pole cortex (FPC) plays key roles in various higher-order functions and is highly developed in non-human primates. An essential missing piece of information is the detailed anatomical connections for finer parcellation of the macaque FPC than provided by the previous tracer results. This is important for understanding the functional architecture of the cerebral cortex. Here, combining cross-validation and principal component analysis, we formed a tractography-based parcellation scheme that applied a machine learning algorithm to divide the macaque FPC (2 males and 6 females) into eight subareas using high-resolution diffusion magnetic resonance imaging with the 9.4T Bruker system, and then revealed their subregional connections. Furthermore, we applied improved hierarchical clu

SUBMITTER: He B 

PROVIDER: S-EPMC7719154 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature