Experimental assessment of microwave ablation computational modeling with MR thermometry.

ABSTRACT:

Purpose

Computational models are widely used during the design and characterization of microwave ablation (MWA) devices, and have been proposed for pretreatment planning. Our objective was to assess three-dimensional (3D) transient temperature and ablation profiles predicted by MWA computational models with temperature profiles measured experimentally using magnetic resonance (MR) thermometry in ex vivo bovine liver.

Materials and methods

We performed MWA in ex vivo tissue under MR guidance using a custom, 2.45 GHz water-cooled applicator. MR thermometry data were acquired for 2 min prior to heating, during 5-10 min microwave exposures, and for 3 min following heating. Fiber-optic temperature sensors were used to validate the accuracy of MR temperature measurements. A total

SUBMITTER: Faridi P 

PROVIDER: S-EPMC7719571 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature