Risk factors for severe COVID-19 in middle-aged patients without comorbidities: a multicentre retrospective study.

ABSTRACT:

Background

Information regarding characteristics and risk factors of COVID-19 amongst middle-aged (40-59 years) patients without comorbidities is scarce.

Methods

We therefore conducted this multicentre retrospective study and collected data of middle-aged COVID-19 patients without comorbidities at admission from three designated hospitals in China.

Results

Among 119 middle-aged patients without comorbidities, 18 (15.1%) developed into severe illness and 5 (3.9%) died in hospital. ARDS (26, 21.8%) and elevated D-dimer (36, 31.3%) were the most common complications, while other organ complications were relatively rare. Multivariable regression showed increasing odds of severe illness associated with neutrophil to lymphocyte ratio (NLR, OR, 11.238; 95% CI 1.110-1.382; p 

SUBMITTER: Wang P 

PROVIDER: S-EPMC7719726 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature