Cannabinoids, Inner Ear, Hearing, and Tinnitus: A Neuroimmunological Perspective.

ABSTRACT: Cannabis has been used for centuries for recreational and therapeutic purposes. Whereas, the recreative uses are based on the psychotropic effect of some of its compounds, its therapeutic effects range over a wide spectrum of actions, most of which target the brain or the immune system. Several studies have found cannabinoid receptors in the auditory system, both at peripheral and central levels, thus raising the interest in cannabinoid signaling in hearing, and especially in tinnitus, which is affected also by anxiety, memory, and attention circuits where cannabinoid effects are well described. Available studies on animal models of tinnitus suggest that cannabinoids are not likely to be helpful in tinnitus treatment and could even be harmful. However, the pharmacology of cannabinoids is v

SUBMITTER: Perin P 

PROVIDER: S-EPMC7719758 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature