Evidence accumulation for value computation in the prefrontal cortex during decision making.

ABSTRACT: A key step of decision making is to determine the value associated with each option. The evaluation process often depends on the accumulation of evidence from multiple sources, which may arrive at different times. How evidence is accumulated for value computation in the brain during decision making has not been well studied. To address this problem, we trained rhesus monkeys to perform a decision-making task in which they had to make eye movement choices between two targets, whose reward probabilities had to be determined with the combined evidence from four sequentially presented visual stimuli. We studied the encoding of the reward probabilities associated with the stimuli and the eye movements in the orbitofrontal (OFC) and the dorsolateral prefrontal (DLPFC) cortices during the decisio

SUBMITTER: Lin Z 

PROVIDER: S-EPMC7720192 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature