Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis.

ABSTRACT:

Background

The benefits of extracorporeal membrane oxygenation (ECMO) in children with sepsis remain controversial. Current guidelines on management of septic shock in children recommend consideration of ECMO as salvage therapy. We sought to review peer-reviewed publications on effectiveness of ECMO in children with sepsis.

Methods

Studies reporting on mortality in children with sepsis supported with ECMO, published in PubMed, Scopus and Embase from 1972 till February 2020, were included in the review. This study was done in adherence to Preferred Reporting Items for Systematic Review and Meta-Analysis statement after registering the review protocol with PROSPERO. Study eligibility was independently assessed by two authors and disagreements resolved by a third author. Public

SUBMITTER: Ramanathan K 

PROVIDER: S-EPMC7720382 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature