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The exercise pressor reflex and chemoreflex interaction: cardiovascular implications for the exercising human.


ABSTRACT:

Key points

Although the exercise pressor reflex (EPR) and the chemoreflex (CR) are recognized for their sympathoexcitatory effect, the cardiovascular implication of their interaction remains elusive. We quantified the individual and interactive cardiovascular consequences of these reflexes during exercise and revealed various modes of interaction. The EPR and hypoxia-induced CR interaction is hyper-additive for blood pressure and heart rate (responses during co-activation of the two reflexes are greater than the summation of the responses evoked by each reflex) and hypo-additive for peripheral haemodynamics (responses during co-activation of the reflexes are smaller than the summated responses). The EPR and hypercapnia-induced CR interaction results in a simple addition of the indi

SUBMITTER: Wan HY 

PROVIDER: S-EPMC7720421 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature