Characteristics of Asthma-related Nocturnal Cough: A Potential New Digital Biomarker.

ABSTRACT:

Introduction

The nature of nocturnal cough is largely unknown. It might be a valid marker for asthma control but very few studies characterized it as a basis for better defining its role and its use as clinical marker. This study investigated prevalence and characteristics of nocturnal cough in asthmatics over the course of four weeks.

Methods

In two centers, 94 adult patients with physician-diagnosed asthma were recruited. Patient-reported outcomes and nocturnal sensor data were collected by a smartphone with a chat-based study app.

Results

Patients coughed in 53% of 2212 nights (range: 0-345 coughs/night). Median coughs per hour were 0 (IQR 0-1). Nocturnal cough rates showed considerable inter-individual variance. The highest counts were measured in the first 30 min

SUBMITTER: Rassouli F 

PROVIDER: S-EPMC7721277 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature