The Impact of Age and Pathogens Type on the Gut Microbiota in Infants with Diarrhea in Dalian, China.

ABSTRACT:

Objective

Diarrhea in infants is a serious gastrointestinal dysfunction characterized by vomiting and watery bowel movements. Without proper treatment, infants will develop a dangerous electrolyte imbalance. Diarrhea is accompanied by intestinal dysbiosis. This study compared the gut microbiota between healthy infants and diarrheic infants. It also investigated the effects of age and pathogen type on the gut microbiota of infants with diarrhea, providing data for the proper treatment for diarrhea in infants.

Materials and methods

DNA was collected from the fecal samples of 42 Chinese infants with diarrhea and 37 healthy infants. The healthy infants and infants with diarrhea were divided into four age groups: 0-120, 120-180, 180-270, and 270-365 days. Using PCR and 16S rRNA h

SUBMITTER: Fan Q 

PROVIDER: S-EPMC7721492 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature