Knowledge, motivations, expectations, and traits of an African, African-American, and Afro-Caribbean sequencing cohort and comparisons to the original ClinSeq^® cohort.

ABSTRACT:

Purpose

Racial minority populations are underrepresented in genomics research. This study enrolled African-descended individuals in a sequencing study and reported their characteristics.

Methods

We purposively recruited 467 individuals self-identified as African, African American, or Afro-Caribbean to the ClinSeq^® study and surveyed them about knowledge, motivations, expectations, and traits. Summary statistics were calculated and compared with data from the study's original cohort, which was primarily White and self-referred.

Results

Recruitment took five years and 83% of enrollees completed the survey. Participants had modest knowledge about benefits and limitations of sequencing (x̅s = 5.1, ranges: 0-10), and less than the original cohort (x̅ = 7.5 and 7

SUBMITTER: Lewis KL 

PROVIDER: S-EPMC7721818 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature