Preventive malaria treatment among school-aged children in sub-Saharan Africa: a systematic review and meta-analyses.

ABSTRACT:

Background

The burden of malaria infection in sub-Saharan Africa among school-aged children aged 5-15 years is underappreciated and represents an important source of human-to-mosquito transmission of Plasmodium falciparum. Additional interventions are needed to control and eliminate malaria. We aimed to assess whether preventive treatment of malaria might be an effective means of reducing P falciparum infection and anaemia in school-aged children and lowering parasite transmission.

Methods

In this systematic review and two meta-analyses, we searched the online databases PubMed, Embase, Cochrane CENTRAL, and Clinicaltrials.gov for intervention studies published between Jan 1, 1990, and Dec 14, 2018. We included randomised studies that assessed the effect of antimalarial treat

SUBMITTER: Cohee LM 

PROVIDER: S-EPMC7721819 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature