Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.

ABSTRACT: Despite tremendous gains in the molecular understanding of exocrine pancreatic cancer, the prognosis for this disease remains very poor, largely because of delayed disease detection and limited effectiveness of systemic therapies. Both incidence rates and mortality rates for pancreatic cancer have increased during the past decade, in contrast to most other solid tumor types. Recent improvements in multimodality care have substantially improved overall survival, local control, and metastasis-free survival for patients who have localized tumors that are amenable to surgical resection. The widening gap in prognosis between patients with resectable and unresectable or metastatic disease reinforces the importance of detecting pancreatic cancer sooner to improve outcomes. Furthermore, the develo

SUBMITTER: Grossberg AJ 

PROVIDER: S-EPMC7722002 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature