Low-dose aspirin in reproductive health: effects on menstrual cycle characteristics.

ABSTRACT:

Objective

To estimate the effect of daily 81 mg low-dose aspirin (LDA) on menstrual cycle length and hormone profiles.

Design

Secondary analysis of a trial evaluating the effect of daily LDA or placebo on live birth among women with one or two previous pregnancy losses.

Setting

University medical centers.

Patient(s)

A total of 915 regularly menstruating women who had at least one menstrual cycle (3,190 total cycles) in which pregnancy did not occur.

Intervention(s)

Randomized allocation to LDA versus placebo.

Main outcome measure(s)

Menstrual cycle length and follicular and luteal phases were measured. Urinary pregnanediol glucuronide, follicle-stimulating hormone, luteinizing hormone, and estrone-3-glucuronide were assessed up to six times during

SUBMITTER: Evans MB 

PROVIDER: S-EPMC7722096 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature