Sex-specific associations between lipids and cognitive decline in the middle-aged and elderly: a cohort study of Chinese adults.

ABSTRACT:

Background

Studies regarding the lipid-cognition relationship have increasingly gained popularity but have generated much mixed results. To date, few studies have focused on the difference between sexes.

Methods

This study included 6792 Chinese adults aged over 45 years (women, 48.56%; mean age, 57.28 years), who were free of severe conditions known to affect cognitive function at the baseline (2011). Blood concentrations of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), and triglycerides (TG) were assessed at baseline, and both continuous and categorical values were used in final analyses. Global cognitive functions were assessed by the word recall test and the mental status test in 2011, 2013, and 2015, re

SUBMITTER: Liu L 

PROVIDER: S-EPMC7722300 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature