Association of breast cancer with MRI background parenchymal enhancement: the IMAGINE case-control study.

ABSTRACT:

Background

Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) may be associated with breast cancer risk, but previous studies of the association are equivocal and limited by incomplete blinding of BPE assessment. In this study, we evaluated the association between BPE and breast cancer based on fully blinded assessments of BPE in the unaffected breast.

Methods

The Imaging and Epidemiology (IMAGINE) study is a multicenter breast cancer case-control study of women receiving diagnostic, screening, or follow-up breast MRI, recruited from three comprehensive cancer centers in the USA. Cases had a first diagnosis of unilateral breast cancer and controls had no history of or current breast cancer. A single board-certified breast radiologist with 12 

SUBMITTER: Watt GP 

PROVIDER: S-EPMC7722419 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature