The relationship between social risk factors and latent tuberculosis infection among individuals residing in England: a cross-sectional study.

ABSTRACT:

Objective

To investigate the relationship between social risk factors and latent tuberculosis infection (LTBI) among individuals who are eligible for LTBI screening in the United Kingdom (UK).

Methods

This cross-sectional study used data collected in the UK Prognostic Evaluation of Diagnostic Interferon-Gamma Release Assays (IGRAs) Consortium Study which enrolled 9176 recent tuberculosis (TB) contacts and migrants at National Health Service (NHS) facilities and community settings in the UK. The study outcome was LTBI (positive IGRA test (QuantiFERON-TB Gold In-Tube or T-SPOT.TB)). The main exposures were history of smoking, history of substance misuse, homelessness, prison stay and socioeconomic deprivation.

Results

4914 (56.2%) individuals resided in the most deprive

SUBMITTER: Lule SA 

PROVIDER: S-EPMC7722758 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature