A multi-country study of prevalence and early childhood mortality among children with omphalocele.

ABSTRACT:

Background

Omphalocele is the second most common abdominal birth defect and often occurs with other structural and genetic defects. The objective of this study was to determine omphalocele prevalence, time trends, and mortality during early childhood, by geographical region, and the presence of associated anomalies.

Methods

We conducted a retrospective study with 23 birth defect surveillance systems in 18 countries who are members of the International Clearinghouse for Birth Defects Surveillance and Research that submitted data on cases ascertained from 2000 through 2012, approximately 16 million pregnancies were surveyed that resulted in live births, stillbirths, or elective terminations of pregnancy for fetal anomalies (ETOPFA) and cases with omphalocele were included. Ove

SUBMITTER: Nembhard WN 

PROVIDER: S-EPMC7722785 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature