Patient and public perspectives on cell and gene therapies: a systematic review.

ABSTRACT: Cell and gene therapies offer opportunities for treating disease with potential to restore function, and cure disease. However, they are not without risk and pose complex logistical, economic, ethical and social challenges for health systems. Here we report our systematic review of the current evidence on patient and public knowledge and perspectives of cell and gene therapies, to inform future research, education and awareness raising activities. We screened 10,735 titles and abstracts, and evaluated the full texts of 151 publications. The final selection was 35 publications. Four themes were generated from the narrative synthesis of the study findings namely: (1) Knowledge and understanding of cell and gene therapies, (2) Acceptance of cell and gene therapies (3) Understanding of risk an

SUBMITTER: Aiyegbusi OL 

PROVIDER: S-EPMC7722871 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature