The efficacy of treating patients with non-metastatic gastric linitis plastica using surgery with chemotherapy and/or radiotherapy.

ABSTRACT:

Background

To explore the efficacy of treatment strategies for non-metastatic gastric linitis plastica (GLP).

Methods

Patients with non-metastatic GLP from 2004 to 2014 were identified from the National Cancer Database (NCDB). We compared overall survival (OS) of those patients who received different treatments, including surgery alone, a combination of surgery with chemotherapy and/or radiotherapy (S + C/R), chemotherapy and/or radiotherapy (C/R), and no treatment.

Results

The cohort included 474 patients with non-metastatic GLP. Overall, the median survival was significantly different among four groups (13.90 months in S + C/R, 8.38 months in surgery alone, 8.94 months in C/R and 2.50 months in no treatment). Then, we compared the efficacy of surgery alone and surge

SUBMITTER: Song X 

PROVIDER: S-EPMC7723551 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature