Lung emphysema and lung cancer: what do we know about it?

ABSTRACT: Emphysema and lung cancer (LC) are two diseases which share common risk factors, e.g., smoking. In recent years, many studies have sought to analyse this association. By way of illustration, we conducted a review of the scientific literature of the studies published to date, whose main designated aim was to demonstrate the relationship between emphysema and LC, and this association's influence on the histology, prognosis and molecular mechanisms responsible. We included over 40 studies (ranging from case-control and cohort studies to systematic reviews and meta-analyses), which highlight the association between emphysema and LC, independently of smoking habit. These studies also report a possible influence on histology, with adenocarcinoma being the most frequent lineage, and an associatio

SUBMITTER: Tubio-Perez RA 

PROVIDER: S-EPMC7723574 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature