Network segregation varies with neural distinctiveness in sensorimotor cortex.

ABSTRACT: Normal aging is associated with declines in sensorimotor function. Previous studies have linked age-related behavioral declines to decreases in neural differentiation (i.e., dedifferentiation), including decreases in the distinctiveness of neural activation patterns and in the segregation of large-scale neural networks at rest. However, no studies to date have explored the relationship between these two neural measures and whether they explain the same aspects of behavior. To investigate these issues, we collected a battery of sensorimotor behavioral measures in older and younger adults and estimated (a) the distinctiveness of neural representations in sensorimotor cortex and (b) sensorimotor network segregation in the same participants. Consistent with prior findings, sensorimotor represe

SUBMITTER: Cassady K 

PROVIDER: S-EPMC7723993 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature