Loci Associated With Antibody Response in Feral Swine (Sus scrofa) Infected With Brucella suis.

ABSTRACT: Feral swine (Sus scrofa) are a destructive invasive species widespread throughout the United States that disrupt ecosystems, damage crops, and carry pathogens of concern for the health of domestic stock and humans including Brucella suis-the causative organism for swine brucellosis. In domestic swine, brucellosis results in reproductive failure due to abortions and infertility. Contact with infected feral swine poses spillover risks to domestic pigs as well as humans, companion animals, wildlife, and other livestock. Genetic factors influence the outcome of infectious diseases; therefore, genome wide association studies (GWAS) of differential immune responses among feral swine can provide an understanding of disease dynamics and inform management to prevent the spillover of b

SUBMITTER: Pierce CF 

PROVIDER: S-EPMC7724110 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature