Assessment of extraintestinal manifestations in inflammatory bowel diseases: A systematic review and a proposed guide for clinical trials.

ABSTRACT:

Background and aims

Extraintestinal manifestations are common in inflammatory bowel disease patients, although there are few data available on their diagnosis, management and follow-up. We systematically reviewed the literature evidence to evaluate tools and investigations used for the diagnosis and for the assessment of the treatment response in inflammatory bowel disease patients with extraintestinal manifestations.

Methods

We searched in PubMed, Embase and Web of Science from January 1999-December 2019 for all interventional and non-interventional studies published in English assessing diagnostic tools and investigations used in inflammatory bowel disease patients with extraintestinal manifestations.

Results

Forty-five studies (16 interventional and 29 non-interven

SUBMITTER: Guillo L 

PROVIDER: S-EPMC7724545 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature