Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China: A Meta-Analysis.

ABSTRACT:

Background

 The aim of this meta-analysis is to assess the prevalence of coagulation dysfunction in Chinese COVID-19 patients and to determine the association of coagulopathy with the severity and prognosis of COVID-19.

Methods

 A meta-analysis of the prevalence of different abnormal coagulation indicators in COVID-19 patients in China was performed. The difference of coagulation indicators and the incidence of DIC were compared between severe cases and nonsevere cases as well as nonsurvivors and survivors, respectively.

Results

 A total of 22 Chinese studies involving 4,889 confirmed COVID-19 inpatients were included. The average D-dimer value of COVID-19 patients is 0.67 µg/mL (95% confidence interval [CI]: 0.56-0.78), and 29.3% (95% CI: 20.1-38.5%) of patients show

SUBMITTER: Jin S 

PROVIDER: S-EPMC7724576 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature