Differential vector competence of Ornithodoros soft ticks for African swine fever virus: What if it involves more than just crossing organic barriers in ticks?

ABSTRACT:

Background

Several species of soft ticks in genus Ornithodoros are known vectors and reservoirs of African swine fever virus (ASFV). However, the underlying mechanisms of vector competence for ASFV across Ornithodoros species remain to be fully understood. To that end, this study compared ASFV replication and dissemination as well as virus vertical transmission to descendants between Ornithodoros moubata, O. erraticus, and O. verrucosus in relation to what is known about the ability of these soft tick species to transmit ASFV to pigs. To mimic the natural situation, a more realistic model was used where soft ticks were exposed to ASFV by allowing them to engorge on viremic pigs.

Methods

Ornithodoros moubata ticks were infected with the ASFV strains Liv13/33 (genotype I) or G

SUBMITTER: Pereira De Oliveira R 

PROVIDER: S-EPMC7725119 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature