Transmissibility of COVID-19 depends on the viral load around onset in adult and symptomatic patients.

ABSTRACT:

Objective

To investigate the relationship between viral load and secondary transmission in novel coronavirus disease 2019 (COVID-19).

Methods

Epidemiological and clinical data were obtained from immunocompetent laboratory-confirmed patients with COVID-19 who were admitted to and/or from whom viral loads were measured at Toyama University Hospital. Using a case-control approach, index patients who transmitted the disease to at least one other patient were analysed as "cases" (index patients) compared with patients who were not the cause of secondary transmission (non-index patients, analysed as "controls"). The viral load time courses were assessed between the index and non-index symptomatic patients using non-linear regression employing a standard one-phase decay model.

R

SUBMITTER: Kawasuji H 

PROVIDER: S-EPMC7725311 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature