Geographically structured genomic diversity of non-human primate-infecting Treponema pallidum subsp. pertenue.

ABSTRACT: Many non-human primate species in sub-Saharan Africa are infected with Treponema pallidum subsp. pertenue, the bacterium causing yaws in humans. In humans, yaws is often characterized by lesions of the extremities and face, while T. pallidum subsp. pallidum causes venereal syphilis and is typically characterized by primary lesions on the genital, anal or oral mucosae. It remains unclear whether other T. pallidum subspecies found in humans also occur in non-human primates and how the genomic diversity of non-human primate T. pallidum subsp. pertenue lineages is distributed across hosts and space. We observed orofacial and genital lesions in sooty mangabeys (Cercocebus atys) in Taï National Park, Côte d'Ivoire and collected swabs and bi

SUBMITTER: Mubemba B 

PROVIDER: S-EPMC7725339 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature