Diffusion-regularized susceptibility tensor imaging (DRSTI) of tissue microstructures in the human brain.

ABSTRACT: Susceptibility tensor imaging (STI) has been proposed as an alternative to diffusion tensor imaging (DTI) for non-invasive in vivo characterization of brain tissue microstructure and white matter fiber architecture, potentially benefitting from its high spatial resolution. In spite of different biophysical mechanisms, animal studies have demonstrated white matter fiber directions measured using STI to be reasonably consistent with those from diffusion tensor imaging (DTI). However, human brain STI is hampered by its requirement of acquiring data at more than 10 head rotations and a complicated processing pipeline. In this paper, we propose a diffusion-regularized STI method (DRSTI) that employs a tensor spectral decomposition constraint to regularize the STI solution using the fiber direct

SUBMITTER: Bao L 

PROVIDER: S-EPMC7725957 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature