Comparative analysis of clinical features of SARS-CoV-2 and adenovirus infection among children.

ABSTRACT:

Background

The new emerging coronavirus disease 2019 (COVID-19) overall shares similar symptoms with other common respiratory viral infections. We aimed in this study to compare COVID-19 and human adenovirus (HAdV) infections in pediatric patients regarding the frequencies of major clinical symptoms and the potential disparities in laboratory and imaging parameters.

Methods

Following a case-control-like design, we built 72 age-matched pediatric COVID-19 and HAdV patient pairs. Their early symptoms and laboratory and imaging characteristics were then retrieved and compared.

Results

Fever and cough were the most common symptoms for both infections but were seen more often in HAdV than in COVID-19 patients (92% vs. 66% and 60% vs. 18%, respectively). Compared with COVID-

SUBMITTER: Li K 

PROVIDER: S-EPMC7726278 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature