A three-dimensional modeling method for quantitative photoacoustic breast imaging with handheld probe.

ABSTRACT: By providing complementary functional information, photoacoustic (PA) breast imaging based on the handheld ultrasound (US) probe has demonstrated promising potential for breast cancer diagnosis. However, the quantitative PA imaging primarily relies on the knowledge of the optical fluence distribution in the three-dimensional (3D) heterogeneous breast tissue. Previous studies based on the handheld system generally provided two-dimensional (2D) B-scan results, which contains limited anatomical information of the tissue and the lesion. This study proposed a method to perform 3D modeling of the photon transportation for dual-modality PA/US system based on the local 3D breast anatomical information by scanning US probe. Then the calculated optical fluence distribution can be used for PA imaging

SUBMITTER: Han T 

PROVIDER: S-EPMC7726342 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature