Association of Neoadjuvant Chemotherapy With Overall Survival in Women With Metastatic Endometrial Cancer.

ABSTRACT:

Importance

Although primary debulking surgery (PDS) is often considered the criterion standard for treatment of stage IV endometrial cancer, PDS is associated with significant morbidity and poor survival. Neoadjuvant chemotherapy (NACT) has been proposed as an alternative treatment strategy.

Objective

To determine the use of and outcomes associated with NACT for women with stage IV endometrial cancer.

Design, setting, and participants

This cohort study used the National Cancer Database to identify women with stage IV endometrial cancer treated from January 1, 2010, to December 31, 2015. The cohort was limited to women aged 70 years or younger with minimal comorbidity (comorbidity score = 0). Women were stratified based on receipt of NACT or PDS. A propensity score ana

SUBMITTER: Tobias CJ 

PROVIDER: S-EPMC7726635 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature