Dose-response relationship between protein intake and muscle mass increase: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT: Lean body mass is essential for health, yet consensus regarding the effectiveness of protein interventions in increasing lean body mass is lacking. The aim of this systematic review was to evaluate the dose-response relationship of the effects of protein intake on lean body mass. The PubMed and Ichushi-Web databases were searched electronically, and reference lists of the literature included here and in other meta-analyses were searched manually. Randomized controlled trials evaluating the effects of protein intake on lean body mass were included. Two authors independently screened the abstracts; 5 reviewed the full texts. A total of 5402 study participants from 105 articles were included. In the multivariate spline model, the mean increase in lean body mass associated with an increase in

SUBMITTER: Tagawa R 

PROVIDER: S-EPMC7727026 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature