Normal Olfactory Functional Connectivity Despite Lifelong Absence of Olfactory Experiences.

ABSTRACT: Congenital blindness is associated with atypical morphology and functional connectivity within and from visual cortical regions; changes that are hypothesized to originate from a lifelong absence of visual input and could be regarded as a general (re) organization principle of sensory cortices. Challenging this is the fact that individuals with congenital anosmia (lifelong olfactory sensory loss) display little to no morphological changes in the primary olfactory cortex. To determine whether olfactory input from birth is essential to establish and maintain normal functional connectivity in olfactory processing regions, akin to the visual system, we assessed differences in functional connectivity within the olfactory cortex between individuals with congenital anosmia (n = 33) and matched co

SUBMITTER: Peter MG 

PROVIDER: S-EPMC7727390 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature