Selenium modifies associations between multiple metals and neurologic symptoms in Gulf states residents.

ABSTRACT:

Background

Metals have been shown to have a wide range of neurologic effects across the life course, but most studies consider neurodevelopment or neurodegenerative diseases in older adults. We investigated exposure to metals during adulthood in association with subclinical neurologic endpoints, considering the metals individually and as a mixture, and potential interactions among exposures.

Methods

We measured blood levels of cadmium, lead, mercury, manganese, and selenium in 1007 Gulf state residents and estimated cross-sectional associations between ranked levels of blood metals and the presence of self-reported neurologic symptoms. Single pollutant models were mutually adjusted for other metals and we used quantile g-computation to evaluate associations with exposure to

SUBMITTER: Werder EJ 

PROVIDER: S-EPMC7727467 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature