Prospective study of a diabetes risk reduction diet and the risk of breast cancer.

ABSTRACT:

Background

Hyperinsulinemia and higher insulin-like growth factors may increase breast cancer risk. We evaluated a diabetes risk reduction diet (DRRD) and breast cancer risk.

Objectives

We prospectively evaluated the association between adherence to a DRRD and the incidence of breast cancer.

Methods

We followed 88,739 women from the Nurses' Health Study (NHS; 1980-2016) and 93,915 women from the NHSII (1991-2017). Incident breast cancer cases (n = 11,943) were confirmed with medical records, and subtypes were determined by tissue microarray data and pathology reports. Information on diet and breast cancer risk factors was repeatedly ascertained in follow-up questionnaires. A DRRD score was derived with 9 factors: lower glycemic index of diet; lower intakes of trans fa

SUBMITTER: Kang JH 

PROVIDER: S-EPMC7727476 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature