Associations of sodium and potassium consumption with the gut microbiota and host metabolites in a population-based study in Chinese adults.

ABSTRACT:

Background

There is increasing evidence that sodium consumption alters the gut microbiota and host metabolome in murine models and small studies in humans. However, there is a lack of population-based studies that capture large variations in sodium consumption as well as potassium consumption.

Objective

We examined the associations of energy-adjusted dietary sodium (milligrams/kilocalorie), potassium, and sodium-to-potassium (Na/K) ratio with the microbiota and plasma metabolome in a well-characterized Chinese cohort with habitual excessive sodium and deficient potassium consumption.

Methods

We estimated dietary intakes from 3 consecutive validated 24-h recalls and household inventories. In 2833 adults (18-80 y old, 51.2% females), we analyzed microbial (genus-level 1

SUBMITTER: Wang Y 

PROVIDER: S-EPMC7727480 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature