Electron Attachment Studies with the Potential Radiosensitizer 2-Nitrofuran.

ABSTRACT: Nitrofurans belong to the class of drugs typically used as antibiotics or antimicrobials. The defining structural component is a furan ring with a nitro group attached. In the present investigation, electron attachment to 2-nitrofuran (C₄H₃NO₃), which is considered as a potential radiosensitizer candidate for application in radiotherapy, has been studied in a crossed electron-molecular beams experiment. The present results indicate that low-energy electrons with kinetic energies of about 0-12 eV effectively decompose the molecule. In total, twelve fragment anions were detected within the detection limit of the apparatus, as well as the parent anion of 2-nitrofuran. One major resonance region of ≈0-5 eV is observed in which the most abundant anions NO_2<

SUBMITTER: Saqib M 

PROVIDER: S-EPMC7727711 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature