Technical Note: On the spatial correlation between robust CT-ventilation methods and SPECT ventilation.

ABSTRACT:

Purpose

The computed tomography (CT)-derived ventilation imaging methodology employs deformable image registration (DIR) to recover respiratory motion-induced volume changes from an inhale/exhale CT image pair, as a surrogate for ventilation. The Integrated Jacobian Formulation (IJF) and Mass Conserving Volume Change (MCVC) numerical methods for volume change estimation represent two classes of ventilation methods, namely transformation based and intensity (Hounsfield Unit) based, respectively. Both the IJF and MCVC methods utilize subregional volume change measurements that satisfy a specified uncertainty tolerance. In previous publications, the ventilation images resulting from this numerical strategy demonstrated robustness to DIR variations. However, the reduced measurement unc

SUBMITTER: Castillo E 

PROVIDER: S-EPMC7727923 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature