Antiviral Therapies for Herpesviruses: Current Agents and New Directions.

ABSTRACT:

Purpose

The objective of this review was to summarize the recent literature describing the current burden of disease due to herpesviruses in the antiviral and transplant era; describe mechanisms of action of antiviral agents and the development of resistance; summarize the literature of recent antiviral agents brought to market as well as agents under development; and to present literature on future strategies for herpesvirus therapeutics.

Methods

An extensive search of the medical literature related to antiherpesviral therapy was conducted to compose this narrative review. Literature searches were performed via PubMed and ultimately 137 articles were included as most relevant to the scope of this article.

Findings

Herpesviruses are a family of DNA viruses that are ub

SUBMITTER: Poole CL 

PROVIDER: S-EPMC7728158 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature