Prognostic value of plasma pentraxin 3 levels in patients with septic shock admitted to intensive care.

ABSTRACT:

Objective

To evaluate the usefulness of a new marker, pentraxin, as a prognostic marker in septic shock patients.

Materials and methods

Single-centre prospective observational study that included all consecutive patients 18 years or older who were admitted to the intensive care unit (ICU) with septic shock. Serum levels of procalcitonin (PCT), C-reactive protein (CRP) and pentraxin (PTX3) were measured on ICU admission.

Results

Seventy-five septic shock patients were included in the study. The best predictors of in-hospital mortality were the severity scores: SAPS II (AUC = 0.81), SOFA (AUC = 0.79) and APACHE II (AUC = 0.73). The ROC curve for PTX3 (ng/mL) yielded an AUC of 0.70, higher than the AUC for PCT (0.43) and CRP (0.48), but lower than lactate (0.79). Adding

SUBMITTER: Perez-San Martin S 

PROVIDER: S-EPMC7728227 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature