Realistic 4D MRI abdominal phantom for the evaluation and comparison of acquisition and reconstruction techniques.

ABSTRACT:

Purpose

This work presents a 4D numerical abdominal phantom, which includes T₁ and T₂ relaxation times, proton density fat fraction, perfusion, and diffusion, as well as respiratory motion for the evaluation and comparison of acquisition and reconstruction techniques.

Methods

The 3D anatomical mesh models were non-rigidly scaled and shifted by respiratory motion derived from an in vivo scan. A time series of voxelized 3D abdominal phantom images were obtained with contrast determined by the tissue properties and pulse sequence parameters. Two example simulations: (1) 3D T₁ mapping under breath-hold and free-breathing acquisition conditions and (2) two different reconstruction techniques for accelerated 3D dynamic contrast-enhanced MRI, are pr

SUBMITTER: Lo WC 

PROVIDER: S-EPMC7728431 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature