The effect of soy isoflavones on arterial stiffness: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Purpose

Some but not all randomized controlled trials (RCTs) of soy isoflavones showed their beneficial effect on arterial stiffness, a predictor of cardiovascular events, dementia, and all-cause mortality, independent of traditional risk factors. To test the hypothesis that supplementation of soy isoflavones reduces arterial stiffness, we performed a systematic review and meta-analysis of RCTs of soy isoflavones on arterial stiffness.

Methods

The protocol of this systematic review was registered with PROSPERO (CRD42019126128) and written in accordance with PRISMA. The PubMed, Embase, and clinicaltrials.gov databases were searched using the following criteria: human subjects, soy isoflavones as intervention, and arterial stiffness as primary outcome. A random-effects meta-an

SUBMITTER: Man B 

PROVIDER: S-EPMC7728657 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature