Phenotypic and genetic characterization of differential galacto-oligosaccharide utilization in Lactobacillus plantarum.

ABSTRACT: Several Lactobacillus plantarum strains are marketed as probiotics for their potential health benefits. Prebiotics, e.g., galacto-oligosaccharides (GOS), have the potential to selectively stimulate the growth of L. plantarum probiotic strains based on their phenotypic diversity in carbohydrate utilization, and thereby enhance their health promoting effects in the host in a strain-specific manner. Previously, we have shown that GOS variably promotes the strain-specific growth of L. plantarum. In this study we investigated this variation by molecular analysis of GOS utilization by L. plantarum. HPAEC-PAD analysis revealed two distinct GOS utilization phenotypes in L. plantarum. Linking these phenotypes to the strain-specific genotypes led to the identification of a lac operon encoding a β-ga

SUBMITTER: Fuhren J 

PROVIDER: S-EPMC7728778 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature