Evaluation of image quality with four positron emitters and three preclinical PET/CT systems.

ABSTRACT:

Background

We investigated the image quality of ¹¹C, ⁶⁸Ga, ¹⁸F and ⁸⁹Zr, which have different positron fractions, physical half-lifes and positron ranges. Three small animal positron emission tomography/computed tomography (PET/CT) systems were used in the evaluation, including the Siemens Inveon, RAYCAN X5 and Molecubes β-cube. The evaluation was performed on a single scanner level using the national electrical manufacturers association (NEMA) image quality phantom and analysis protocol. Acquisitions were performed with the standard NEMA protocol for ¹⁸F and using a radionuclide-specific acquisition time for ¹¹C, ⁶⁸Ga and ⁸⁹Zr. Images were assessed using percent recovery coefficient (%RC), perc

SUBMITTER: Teuho J 

PROVIDER: S-EPMC7728905 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature